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Caffarelli C, Cardinale F, Povesi-Dascola C, Dodi I, Mastrorilli V, Ricci G. Use of probiotics in pediatric infectious diseases. Expert Rev Anti Infect Ther 2015;13:1517-35. [ PubMed abstract] Overall, research suggests that the use of multiple probiotic strains in combination as well as of probiotics containing Lactobacillus acidophilus, a mixture of Lactobacillus acidophilus and Bifidobacterium lactis, or Lactobacillus plantarum might reduce total and LDL cholesterol levels. However, more research is needed to confirm these findings. Obesity
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The ProVen Probiotics product range is supported by ongoing research and is being updated continuously.Sairenji T, Collins KL Evans DV. An update on inflammatory bowel disease. Prim Care 2017; 44: 673-92. [ PubMed abstract] You can choose from chewable tablets and powder products, and lower amounts of friendly bacteria with higher levels of vitamins or high bacteria count with specifically selected vitamins.- Individuals receiving inpatient care are at significantly greater risk of developing AAD than individuals receiving outpatient care. Similarly, children younger than 2 years and seniors older than 65 years are at greater risk of developing AAD than other children and adults. Some antibiotics (e.g., erythromycin and penicillin) are associated with AAD more often than others [ 25, 26]. Sun J, Buys N. Effects of probiotics consumption on lowering lipids and CVD risk factors: a systematic review and meta-analysis of randomized controlled trials. Ann Med 2015;47:430-40. [ PubMed abstract] ProVen Probiotics Adult Acidophilus & Bifidus – 50 Billion is an ultra-high-strength friendly bacteria supplement for use alongside antibiotics for adults aged 16+. Each capsule contains 50 billion friendly bacteria and should be taken both alongside and following a course of antibiotics, allowing at least two hours between taking the antibiotics and taking the probiotic capsule.
Pro-Ven Probiotics 50 Billion CFU Shapeline Aids Weight Loss Pro-Ven Probiotics 50 Billion CFU Shapeline Aids Weight Loss
Didari T, Mozaffari S, Nikfar S, Abdollahi M. Effectiveness of probiotics in irritable bowel syndrome: Updated systematic review with meta-analysis. World J Gastroenterol 2015;21:3072-84. [ PubMed abstract] Taken together, these results indicate that the effects of probiotics on body weight and obesity might depend on several factors, including the probiotic strain, dose, and duration as well as certain characteristics of the user, including age, sex, and baseline body weight. Additional research is needed to understand the potential effects of probiotics on body fat, body weight, and obesity in humans. Safety Considerations Probiotics usually exert their effects in the gastrointestinal tract, where they may influence the intestinal microbiota. Probiotics can transiently colonize the human gut mucosa in highly individualized patterns, depending on the baseline microbiota, probiotic strain, and gastrointestinal tract region [ 4]. Borriello SP, Hammes WP, Holzapfel W, Marteau P, Schrezenmeir J, Vaara M, et al. Safety of probiotics that contain lactobacilli or bifidobacteria. Clin Infect Dis 2003;36:775-80. [ PubMed abstract]
Jafarnejad S, Shab-Bidar S, Speakman JR, Parastui K, Daneshi-Maskooni M, Djafarian K. Probiotics reduce the risk of antibiotic-associated diarrhea in adults (18-64 years) but not the elderly (>65 years): a meta-analysis. Nutr Clin Pract 2016;31:502-13. [ PubMed abstract] Taking friendly bacteria such as Acidophilus and Bifidus alongside and following antibiotics may help to maintain a balanced microbiota. Multi-strain ultra-high-strength live bacteria Zmora N, Zilberman-Schapira G, Suez J, Mor U, Dori-Bachash M, Bashiardes S, et al. Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features. Cell 2018;174:1388-405.e21. [ PubMed abstract]
50 Billion per capsule - Pro-Ven Probiotics For Antibiotics – 50 Billion per capsule - Pro-Ven Probiotics
Bosch M, Fuentes MC, Audivert S, Bonachera MA, Peiro S, Cune J. Lactobacillus plantarum CECT 7527, 7528 and 7529: probiotic candidates to reduce cholesterol levels. J Sci Food Agric 2014;94:803-9. [ PubMed abstract] ProVen Probiotics products are supported by more than 30 clinical trials and over ninety other studies and papers. Borgeraas H, Johnson LK, Skattebu J, Hertel JK, Hjelmesaeth J. Effects of probiotics on body weight, body mass index, fat mass and fat percentage in subjects with overweight or obesity: a systematic review and meta-analysis of randomized controlled trials. Obes Rev 2018;19:219-32. [ PubMed abstract] Results of clinical trials that assessed the impact of probiotics on obesity-related endpoints have been inconsistent. One 12-week clinical trial, for example, randomized 210 healthy adults age 35 to 60 years who had large amounts of visceral fat to consume 200 g/day fermented milk containing 10 7, 10 6, or 0 (control) CFU of Lactobacillus gasseri SBT2055 (LG2055) per gram of milk [ 59]. Participants who received 10 7 or 10 6 CFU/g milk of Lactobacillus gasseri experienced significant reductions in visceral fat area (mean reductions of 8.5% and 8.2%, respectively), body mass index, waist and hip circumference, and body fat mass compared with the control group. In another randomized clinical trial, daily supplementation with 3.24 x 10 8 CFU Lactobacillus rhamnosus CGMCC1.3724 for 24 weeks combined with an energy-restricted diet for the first 12 weeks (500 kcal/day less than estimated calorie needs) did not significantly affect weight loss compared with placebo in 125 adults age 18 to 55 years with obesity [ 60]. However, the Lactobacillus supplementation did significantly reduce body weight after 12 weeks (loss of 1.8 kg) and 24 weeks (loss of 2.6 kg) compared with placebo in the 77 female participants.Subgroup analyses showed that the use of probiotics during both the prenatal and postnatal periods significantly reduced the incidence of dermatitis; however, probiotics taken either prenatally only or postnatally only did not. In addition, the effects of probiotic treatment varied by probiotic strain. For example, supplementation with either Lactobacillus rhamnosus or Lactobacillus paracasei significantly reduced the incidence of atopic dermatitis, whereas supplementation with Lactobacillus reuteri or Lactobacillus acidophilus did not. Suzumura EA, Bersch-Ferreira AC, Torreglosa CR, da Silva JT, Coqueiro AY, Kuntz MGF, et al. Effects of oral supplementation with probiotics or synbiotics in overweight and obese adults: a systematic review and meta-analyses of randomized trials. Nutr Rev 2019. [ PubMed abstract]
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The International Scientific Association for Probiotics and Prebiotics advises manufacturers to list the total number of CFUs—ideally for each strain—on the expiration or use by date on the product label [ 74]. The association also suggests that consumers of these supplements avoid products that list the number of CFUs at time of manufacture because this information does not account for declines in CFUs over a product’s lifespan. ReferencesTrusted Customer | Independent review via Feefo Friendly bacteria alongside and following antibiotics If using alongside antibiotics, ensure that ProVen Probiotics Acidophilus & Bifidus – 50 Billion is taken a minimum of 2 hours away from antibiotic intake. Directions for use
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